Why is my dog aggressive and lethargic after a Dexamethasone shot?

Question

Mazikeen just bit at a kid, this is EXTREMELY uncharacteristic of her, she has never been aggressive in any way shape or form. She just got a shot of Dexamethasone today, could that change behavior? She’s been pretty absent since about 5 hours after shot, and very hungry which also not normal. Pet's info: Dog | Boxer | Female | spayed | 8 months and 5 days old | 56.2 lbs

Jennifer Summerfield, DVM CPDT-KA · Accepted Answer

Hi there. Steroids can sometimes cause increased irritability or aggression, so it's possible that the medication might have contributed to her being more grumpy than usual. Dexamethasone generally wears off within 36 hours or so, so if this is the problem, she should be back to her normal self after that.

Why is my dog aggressive and lethargic after a Dexamethasone shot?

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