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My dog is limping and lethargic after shots. What can I do to help?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Large (61lb +) | Male | neutered | 11 years and 10 months old | 65 lbs

Simba (my dog) received vaccinations yesterday (Rabies, Distemper, leptospirosis) and has been limping since. Seems to be a little worse this morning. When feeling around he whimpered when I was feeling around his shoulder on the leg that received the shots. He seems to be more lethargic than normal (lazy dog normally). Should I be concerned? What can I do to help him feel better??

2 Answers

Most Helpful Answer

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Answered By Dr. Melanie, BVSc MS

Veterinarian

Published on November 3rd, 2019

While you can see some pain after receiving vaccines, it should easy in 24-48 hours. Rest Simba. No running, jumping, or playing. Take him out to potty on a leash, and bring him right back in when he's done. Do not feel the area where he got the shots. You can apply a cold compress gently to that area to see if it helps. If he is still this way in the morning, have him seen by a vet.

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    Answered By Lauren Jones VMD

    Veterinarian

    Published on March 3rd, 2019

    I'm sorry to hear that Papo isn't feeling well! Some dogs can experience a bit of lethargy and discomfort at the injection site after vaccinations. You can try applying a warm compress to the sites of his vaccine and microchip administration to see if this helps relieve some discomfort. More serious side effects, such as allergic reactions with facial swelling, hives, vomiting or diarrhea are uncommon, but if he experiences anything along these lines, contact the Petco Pet Education Center, formerly Petcoach in San Marcos or an emergency veterinarian. This discomfort should resolve in the next day or two. I hope that Papo is feeling better soon!

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