Are my dog's weak back legs a side effect of seizure medication?

Question

My St Bernard has recently been prescribed Epiphen 210mg twice a day for seizures and since starting this dose 5 days ago he’s suddenly struggling to get up and has lost strength and co-ordination in his back legs. His own vet thinks it’s an orthopedic concern and isn’t related to the medication, but he was fine before taking this medication. it surely can’t be a coincidence can it? They’ve suggested x-rays and anti-inflamatory’s. I would love a 2nd opinion. Hope to hear from you. Emma. Pet's info: Dog | Saint Bernard | Male | neutered | 175 lbs

Ana M, DVM · Accepted Answer

Thank you for submitting your question regarding Gus. I suspect that the new seizure medication has interfered a bit with his coordination. This is common when starting a seizure medication. In his case, it has likely exacerbated underlying joint disease. So I think his problem is a result of both the drug therapy and his joints. The effects of seizure medications become less pronounced as the animal becomes used to it over a week or two. He could also try another drug to see if he has less side effects. However, with his size many drugs might be cost prohibitive. It would be a good idea to take x-rays. If he has joint disease, it is best to treat it as soon as possible. Typical therapies are weight management, joint supplements and anti-inflammatory pain medication. I hope this information helps!

Are my dog's weak back legs a side effect of seizure medication?

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