My dog has high lipase but normal amylase. Is it pancreatitis?
Updated On September 23rd, 2025
Pet's info: Dog | Mixed Breed | Male | neutered | 2 years and 5 months old | 6 lbs
Does a high Lipase level (2824) on a blood test mean that my dog has pancreatitis if the Amylase level is normal?
3 Answers
Most Helpful Answer
Published on May 17th, 2018
Hi there and thank you for using Petco Pet Education Center, formerly Petcoach to address your concern. Just because a Lipase is elevated does not automatically indicate that a dog has pancreatitis. Serum lipase and even amylase can increase with multiple other causes, not just pancreatitis. This is why it is difficult to diagnose pancreatitis based on these levels alone. If Diesel is symptomatic for pancreatitis with these values, I would have additional testing performed to help confirm pancreatitis. I would even consider an abdominal ultrasound if possible. I hope this helps! Please let me know if you have any other questions or concerns and I would be more than happy to help you further.
3Pet Parents found this answer helpful
Related Answers from Veterinarians
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Published on September 9th, 2019
It depends on the lab reference range of the lab used. A labs reference range for Lipase can be quite variable but it generally is around 200-1800 through Idexx and Antech's normal range is from 77-695. So in any case, your pets value is normal. The best way to help prevent future pancreatitis issues with your pet is to keep him on a low fat diet. I would recommend Hill's I/D low fat for long term management. Best of luck with Rocky moving forward. Take care!
1Pet Parents found this answer helpful
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Published on October 12th, 2019
Pancreas-specific lipase (PSL) is a form of lipase produced only in the pancreas. It is highly specific to the pancreas, and blood values increase only when there is pancreatic inflammation. So if your vet did not run a PSL I would not be worried especially if the dog has no clinical signs. By comparison, serum lipase can come from tissues other than the pancreas so high blood values can occur with conditions other than pancreatitis.
1Pet Parents found this answer helpful
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