My dog's mast cell tumor vanished on prednisone. Is it cured?

Question

I found a small lump on my 4 year old lab/pit mix when I was searching for ticks. It was on his inner thigh and after a fine needle aspiration the vet told me it was a Mast cell Tumor. He’s been ok Prednisone and Benadryl for a week and it’s completely disappeared. What does this mean? Is this a good sign? Could she have misdiagnosed? He’s going back in a couple days for blood work before it gets surgically removed. I’m not sure how they’ll know where it is now! Pet's info: Dog | Mixed Breed Large (61lb +) | Male | neutered | 4 years and 6 months old | 93 lbs

Juliana, DVM · Accepted Answer

I’m sorry Gunner is dealing with this! Mast cell tumors are unfortunately a very common tumor we see. Mast cells are a type of inflammatory cell so we expect tumors to shrink considerably when dogs are on prednisone and Benadryl. I would use a sharpie to mark where the tumor is/was to keep track of it. Surgical excision is the most important part of the treatment plan. And with a successful surgery many dogs do great. Once the tissue is removed your vet will have a lot more information to give you about Gunner s specific mast cell tumor. I hope gunner does very well!

My dog's mast cell tumor vanished on prednisone. Is it cured?

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