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When can I safely use Simparica after Frontline Plus for fleas?

Updated On September 23rd, 2025

Pet's info: Dog | Chihuahua (Smooth Coat) | Male | neutered | 9 lbs

Can you use Simparica with Frontline plus or should I wait until the end of Frontline Plus skin dosing ? At three weeks post Frontline dose now, moved to a condo with a dog park and fleas are a problem

1 Answer

Most Helpful Answer

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Answered By Destini R. Holloway, DVM

Veterinarian

Published on October 4th, 2019

You can safely use one after the other if you wait at least 2 weeks in between applications. So since it has been 3 weeks, then you are ok to switch to Simparica now. I would also recommend treating the condo with a flea fogger purchased from your local Home Depot or Lowe's. Thanks for visiting Petco Pet Education Center, formerly Petcoach and I hope that you get rid of your flea problem soon! Take care.

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