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My dog has Cushing's. Is Vetoryl necessary for mild symptoms?

Updated On September 23rd, 2025

Pet's info: Dog | Poodle | Male | neutered | 11 years and 8 months old | 56 lbs

11.5 yr-old izzy was recently diagnosed with cushing's (most probably pituitary origin). his only symptoms are mild hair loss and fairly marked polydipsia/polyuria. he has some elevated liver enzymes but they've actually been improving without treatment. my vet wants to start him on medication (vetoryl) but i'm hesitant because neither he nor i am bothered by his drinking and peeing a lot, the medication is expensive, has side effects, and has to be monitored closely (he HATES going to the vet).

1 Answer

Most Helpful Answer

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Answered By Linda G, MS, DVM

Veterinarian

Published on April 9th, 2018

Hello. For the most part, Vetoryl is used to control the symptoms of Cushing's by controlling the production of glucocorticoids. Overproduction of glucocorticoids is responsible for the symptoms of excessive drinking & urination but does nothing for the actual tumor growing on his pituitary gland. If Izzy's symptoms are manageable & tolerable then medication is not necessary. This would be your choice. But if his symptoms do get worse, at least consider once a day dosing. Most dogs do very well on twice daily dosing, but once a day can help in many pets. Thanks for using Petco Pet Education Center, formerly Petcoach.

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