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My dog's lipase is high, but not pancreatitis. What else could it be?

Updated On September 23rd, 2025

Pet's info: Dog | Chihuahua (Long Coat) | Male

In which case there is an elevate in lipase(except pancreatitis). My dog often has high lipase but the vet couldn't find the problem .(liver and kidney tests are all fine).He s doing ok( not vomit,diarrhea, or fever or abdominal pain...)i m so worried that ỉt could be another illness..

1 Answer

Most Helpful Answer

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Answered By Dr. Strydom, DVM

Veterinarian

Published on October 12th, 2019

Pancreas-specific lipase (PSL) is a form of lipase produced only in the pancreas. It is highly specific to the pancreas, and blood values increase only when there is pancreatic inflammation. So if your vet did not run a PSL I would not be worried especially if the dog has no clinical signs. By comparison, serum lipase can come from tissues other than the pancreas so high blood values can occur with conditions other than pancreatitis.

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