My dog's seizures returned on zonisamide. Should I up her dose?

Question

My dog started having seizures back in May. She since has been put on zonisamide twice a day to control her seizures. She went 6 weeks without having one since she was first put on zonisamide and had 3 today. Thinking she may have epilepsy. Would epilepsy prevail over the zonisamide? The vet sent her home with instructions to up her dosage of zonisamide. She is also diabetic and takes insulin but her levels were normal after the seizures. Any input? Pet's info: Dog | Mixed Breed Medium (23 - 60lb) | Female | unspayed | 38 lbs

Dr. Melanie, BVSc MS · Accepted Answer

Sometimes the anti-seizure medication needs to be increased to control the seizures, there is a chance they could get worse over time as you've seen. I think upping Mali's dosage is a good idea, and see how this helps her. If it doesn't, take her back into the vet.

My dog's seizures returned on zonisamide. Should I up her dose?

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