My dog has ITP and low platelets. Could it be Ehrlichiosis too?
Updated On September 23rd, 2025
My 8 year old golden retriever was diagnosed yesterday with ITP. Had blood work, x-rays, and an ultrasound. All clear, no masses, no tumors. Was healthy and active just 10 days ago. Symptoms (lethargy, loss of appetite) were noticeable about five days ago and acute Sunday-Monday. Platelet count is 48,000, fever 104. Vet put him on 20mg prednisone but NOT on doxycycline. I think he may have ehrlichiosis.
2 Answers
Most Helpful Answer
Published on September 10th, 2019
The prednisone is appropriate to use as that is what will stop the body from destroying it's platelets. If you are worried about Ehrlichiosis as a possibility then you can ask your vet to test your dog for it. There are two main tests for Ehrlichia: PCR testing for Ehrlichia DNA OR blood testing for Ehrlichia antibodies. Antibody testing has been the main diagnostic for many years but recent availability of PCR testing has changed the approach.
1Pet Parents found this answer helpful
Related Answers from Veterinarians
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Published on August 6th, 2017
Hello and thank you for your post! It sounds like your vet has ruled out quite a bit already with diagnostics. ITP can be frustrating to treat. I do not think the canine advantix would be the cause, however, I suppose it is in the realm of possibilities. Sometimes certain drugs can cause this. Certain antibiotics. A full history of medications prior to the episode of ITP should be considered. If the prednisone and melatonin are not working, your vet may consider other immunosuppressing medications such as azathioprine and cyclosporine. I would keep these platelets checked on a regular basis to ensure they are coming up so that your vet can add on additional medications if needed. If there is no improvement you could always seek a referral to an internal medicine specialist as well. Hope Lacy gets better! If you have any questions or concerns feel free to contact me with any further questions. I am also available via consultation.
1Pet Parents found this answer helpful
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