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My Great Dane puppy is lethargic and won't eat. What should I do?

Updated On September 23rd, 2025

Pet's info: Dog | Great Dane | Female | unspayed | 5 months and 14 days old | 60 lbs

Our Great Dane pup has been lethargic all day and not eating

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1 Answer

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Answered By Ricardo Fernandez, DVM

Veterinarian, Veterinary Oncology Resident

Published on August 7th, 2019

Hi there! Sorry to hear that Rosie is not feeling well. The clinical signs you describe are concerning when they occur in a puppy as they can be seen with serious gastrointestinal infections such as Parvovirus. Other possibilities include intestinal worms and dietary indiscretion, among other possibilities. The sooner these conditions are treated the better the outcome tends to be. For this reason, I recommend that you have Rosie evaluated by your veterinarian to check for these possibilities and to start therapy based on findings. At the very least they can address dehydration if present and start her on anti-nausea medications. Good luck! Keeping my fingers crossed for your girl!

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