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Why is my puppy shivering and lethargic after vaccines and meds?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Small (up to 22lb) | Female | unspayed | 4 months and 17 days old | 8 lbs

My puppy is shivering whining and lethargic. She had the last shot of distemper today also fed her flea treatment and heartworm to night

1 Answer

Most Helpful Answer

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Answered By Ricardo Fernandez, DVM

Veterinarian, Veterinary Oncology Resident

Published on July 1st, 2019

Thanks for using Petco Pet Education Center, formerly Petcoach! Possible side effects after vaccines include pain at the injection site, lethargy, inappetence and general discomfort. This should subside within 1-2 days. If it does not improve or it worsens, have Missy evaluated by a veterinarian for further assessment and treatment. Otherwise, Missy will likely start feeling better shortly. Good luck and best wishes!

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