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Advantix not working. Can I give Nexgard soon after last dose?

Updated On September 23rd, 2025

Pet's info: Dog | Dogue de Bordeaux | Female | spayed | 120 lbs

I used Advantix on my dog last month and again last weekend. It is not working. Is it safe to give him Nexguard so soon after the last Advantix application? (5 days ago)

1 Answer

Most Helpful Answer

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Answered By Dr. Melanie, BVSc MS

Veterinarian

Published on June 27th, 2019

I’m sorry it’s not working! I would give Bruzer Capstar. It’s a one time pill that starts killing fleas in 30 minutes, and it’s safe to give now. Give it once a day until it’s been a week since you applied the Advantix, and then give him the Nexgard. Also be sure to disinfect your home, as fleas live in the environment, not on the dog. Wash his bedding in hot and soapy water, and vacuum all the carpets and furniture. Use a spray like Indorex or a flea bomb to kill all the fleas in the house. I hope this helps!

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