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Is it safe to give my dog Zyrtec and Apoquel together for allergies?

Updated On September 23rd, 2025

Pet's info: Dog | Labrador Retriever | Female | spayed | 7 years and 3 months old | 80 lbs

My dog has been on Apoquel 16 mg once a day for 2 years for allergies. She is really itchy and her eyes are runny about 12 hours after taking the pill. I would like to give her Zyrtec before bed to get her through the night. Will this interact with the Apoquel? She weighs 80 lbs. How much should she take? 5mg or 10 mg?

1 Answer

Most Helpful Answer

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Answered By Jeffrey Milner

Veterinarian

Published on May 30th, 2019

These two medications can be given together without risking any significant interactions. Unfortunately I am not able to give drug dosing recommendations as per guidelines of Petco Pet Education Center, formerly Petcoach, but this information should be readily available in several veterinary drug formularies or by speaking with your primary care veterinarian.

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