Why are my dog's Cushing's symptoms getting worse on Vetoryl?
Updated On September 23rd, 2025
Pet's info: Dog | American Staffordshire Terrier | Male | neutered | 75 lbs
Hi there. My dog was diagnosed last year with a tumor on his pituitary gland, which caused him to get Cushing disease and calcinosis cutie. We have him on Vetroyl. But his symptoms just keep getting worse, constant peeing, eating, isn’t sleeping or letting anyone else sleep. I don’t know what to do at this point.
2 Answers
Most Helpful Answer
Published on May 22nd, 2019
Poor Nemesis. Sometimes pets will need the medication adjusted. I recommend to call your veterinarian and ask if another test is needed to evaluate the blood levels in his body. The test is called an ACTH stimulation test. It has been found that 50% of dogs with Cushing’s disease will also have a urinary tract infection that can only be detected with a urine culture. I recommend to have this test done as well as this will cause constant drinking and urination. Other conditions such as thyroid disease, diabetes or kidney disease can also cause these signs. You must start ruling them out. Best of luck.
2Pet Parents found this answer helpful
Related Answers from Veterinarians
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Published on June 30th, 2017
Vomiting and decreased appetite can be a side effect of Vetoryl. You should really call your vet and give him/her an update. Your vet may want to run an ACTH stimulation test and serum biochemistry, including electrolytes to see if her dose needs to be adjusted. Please call your vet as soon as you can.
1Pet Parents found this answer helpful
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