Why is my dog hiding, lethargic, and breathing fast after Trifexis?

Question

My dog was administered her yearly vaccines and trifexis today. It has been over 4 hours since the trifexis and she is hiding, lethargic and breathing fast. Are these normal symptoms? She has never reacted to trifexis this way. Pet's info: Dog | Mixed Breed Medium (23 - 60lb) | Female | spayed | 3 years and 7 months old | 51 lbs

Dr. Melanie, BVSc MS · Accepted Answer

No, this isn't typical. Keep a close eye on her, and take her back into the vet in the morning if the symptoms persist. If she starts vomiting, has diarrhea, starts having trouble breathing, gets a rash or hives, or her face starts swelling, bring her into an ER vet immediately. Best of luck.

Why is my dog hiding, lethargic, and breathing fast after Trifexis?

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