My dog's enlarged neck lymph node keeps coming back. What's wrong?

Question

enlarged lymph node on left side of neck brought to vet and had x-rays, blood work (including for thyroid) & fine needle aspiration. Fine needle just showed to be lymph tissue. vet prescribed amoxiclav and meloxicam for 14 days. Continued melox. for an extra 7 days. Lump was gone. 3 months (ish) later the lump is back. Called vet, prescribed more amoxiclav and melox. for same duration. Lump still there Brought him back to the vet, he was examined and prescribed same meds. Lump still there! Pet's info: Dog | Caucasian Ovcharka | Male | neutered | 3 years and 4 months old | 150 lbs

Sarah Derksen, DVM · Accepted Answer

Hi. I would recommend getting the cytology either redone again, or do a biopst to try to find the cause. The fact that it responds to antibiotics concerns me there is an infection somewhere that node is draining. I would be suspicious of the mouth/teeth. If cytology or biopsy comes back as reactive or unhelpful, I would plan a dental cleaning and dental xrays to look closer in mouth.

My dog's enlarged neck lymph node keeps coming back. What's wrong?

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