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My dog takes Carprofen. Can he also take Benazepril for kidney health?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Large (61lb +) | Male | neutered | 11 years and 4 months old | 85 lbs

What is the percentage of dogs that have experienced renal injury from taking Carprofen and Benazepril daily. My 85lb Golden/Lab mix, Buddy, has been using Carprofen for 5 years due to arthritic pain. Recently our Vet after extensive testing has determined Buddy is losing protein through his kidneys and has prescribed 20mg of Benazepril 2x per day. Your site and PetMD.com both state there may be Drug interaction. If OK to continue do you think Benazapril is better with or without food. Opinion?

1 Answer

Most Helpful Answer

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Answered By Ana M, DVM

Veterinarian

Published on May 1st, 2019

Thank you for submitting your question regarding Buddy. I have used these medications together in dogs before when necessary. That being said, kidney values, blood pressure and the amount of protein in the urine needs to be closely monitored. I typically will recheck a blood pressure reading within the first week of starting benazapril. Then I will follow up by taking a blood sample several weeks later. Kidney values need followed not only for elevations above normal, but also trends upwards that are still in the normal range. With close monitoring, problems can be identified early and doses or medications can be changed if needed. I hope this information helps!

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