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My dog has seizures. What are safer seizure meds than phenobarbital?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed | Female | spayed | 93 lbs

My 8-year-old German Shepherd/Golden Retriever mix dog (female) has just started having seizures--cause unknown to vet. She has been prescribed phenobarbital 64.9 mg tablets --1 pill every 12 hours. I have been told that this pill can cause liver damage ,so it is no longer used for human seizures. Is there some other drug that would stop the seizures and not damage the dog's liver and would not have other dangerous side effects?

1 Answer

Most Helpful Answer

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Answered By Dr. Melanie, BVSc MS

Veterinarian

Published on April 3rd, 2019

There are other seizure drugs that can be used in dogs such as Keppra, Zonisamide, and Potassium Bromide (which is good in patients with liver problems). You will need to speak to Annie's vet to see if a change in medication is an option for her. Best of luck.

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