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My puppy has a lump and is sore after puppy shots. What helps?

Updated On September 23rd, 2025

Pet's info: Dog | Chihuahua | Male | unneutered | 2 months and 14 days old | 3.2 lbs

I have a small 3.2 lb chihuahua who received his puppy 2 vaccines today. He has a lump the size of a large gumball and cries when he is touched or moved What can I do for pain and swelling?

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3 Answers

Most Helpful Answer

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Answered By Jennifer Summerfield, DVM CPDT-KA

Veterinarian, Certified Dog Trainer

Published on March 31st, 2019

Poor Rocky. A lump at the vaccination site, as well as some soreness and tiredness, are normal after getting a vaccine. If Rocky will let you, you can try holding a warm compress (such as a washcloth soaked in warm water and then wrung out) against the sore area for a few minutes 1-2 times daily until he seems to be feeling better. Usually, most pups are back to normal within a few days :)

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1Pet Parents found this answer helpful

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    Answered By Dr. Melanie, BVSc MS

    Veterinarian

    Published on March 12th, 2017

    It can be normal for puppies to be a little more painful after their vaccines, and Chihuahuas tend to be a more nervous breed and a little more sensitive after having vaccines. He should return to normal in a day or two, but if he does still appear painful after 48 hours, I would have him seen by a vet.

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    Answered By Jennifer Summerfield, DVM CPDT-KA

    Veterinarian, Certified Dog Trainer

    Published on December 27th, 2016

    Poor Vito! Yes, this could certainly be related to the vaccination yesterday - it's very common for puppies to be sore for a day or two in the area where the vaccine was given, just like kids :) If he received the vaccine in his rear end, this could certainly be the reason for the soreness. If so, it should resolve within the next 24-48 hours. If it doesn't, or if he develops any other symptoms, it would be best to have him rechecked by your vet in case something else might be wrong.

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