Why can't dogs process caffeine and theobromine like humans?

Question

Why can't dogs metabolize caffeine and theobromine?

Dr. Melanie, BVSc MS · Accepted Answer

Dogs process theobromine much slower than humans, leading it to build up to toxic levels in their system. Dogs are very sensitive to caffeine. With caffeine, it takes 30 minutes to an hour to reach peak concentrations in their bloodstream and cause signs of clinical toxicity.

Why can't dogs process caffeine and theobromine like humans?

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