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Is Apoquel good for dog anxiety and allergies, or just allergies?

Updated On September 23rd, 2025

Pet's info: Dog | Golden Retriever | Male | neutered | 3 years and 10 months old | 75 lbs

I need info on apoquel: my golden retriever has anxiety and allergies can it treat both and be given daily? He is 75 pounds and mildly/moderately anxious. It doesn’t impact him enough for him to act out but he is high strung and breaths hard because of it. Allergies mostly with eyes and paws. im currently trying Benadryl but I don’t know if that’s a good long term/semi long term solution. Anxiety is most likely separation and just how reactive he is to new things and surprises. Thanks

1 Answer

Most Helpful Answer

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Answered By Makenzie Kurth, DVM

Veterinarian

Published on March 1st, 2019

Thanks for using Petco Pet Education Center, formerly Petcoach. First off, if Benedryl is working for the allergies, I would absolutley stick with that. It is by far the safest and cheapest option. And, it can help some with the anxiety. Talk to your vet to be sure you’re using the right dose though- it’s much higher than a human dose. Secondly, Apoquel is awesome in terms of allergies but will do nothing for anxiety. That being said, if some of the anxiety and heavy breathing is due to being itchy and uncomfortable, that may improve with the apoquel. Hope this helps. Best wishes to you and Rowan!

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