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My cat has Frontline Plus. Can I add a Seresto collar safely?

Updated On September 23rd, 2025

Pet's info: Cat | Mixed Breed | Male | neutered

Hi! Can Frontline Plus and Seresto be safely combined for a medium/large cat? He’s had Frontline Plus administered two weeks ago for fleas, and I’m specifically wondering whether a Seresto collar can safely be used for supemental protection — especially when he goes outside, and while I’m working to get the house flea-free — before the next monthly dose of Frontline. Thanks!

1 Answer

Most Helpful Answer

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Answered By Linda G, MS, DVM

Veterinarian

Published on February 12th, 2019

Hello. Yes, absolutely you can use both, but since the collar lasts 8 months, remove it for a week after you reapply the Frontline Plus. Then you can safely put the collar back on. Thanks for using Petco Pet Education Center, formerly Petcoach.

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