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My dog has resistant ear infections. Can topical Baytril still work?

Updated On September 23rd, 2025

Pet's info: Dog | English Bulldog | Male | unneutered | 8 years and 11 months old | 65 lbs

My English bulldog has a recurrent history of ear infections. Previously he's been on Baytril related to ear infection/perforated eardrum plus saline flushes daily. Then, his lab test showed he's resistant to Baytril. Now he's on Clindamycin. His vet called today and recommended that he be on another topical solution for his ear-- it's something they have to mix up but has Baytril in it. So I questioned it due to the fact he's resistant to it. She said he shouldn't be on oral Baytril vs topical.

1 Answer

Most Helpful Answer

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Answered By Shaneez Wallani, DVM

Veterinarian

Published on February 7th, 2019

Poor Gamble! Resistant ear infections can certainly be very frustrating to treat. In some cases, the compounded ear medications with several medications in them can be effective, even if the individual components are not, and there can indeed be a difference between effectiveness of oral vs topical medications. You can always ask your vet for a referral to a veterinary dermatologist if the problem persists, and your vet may also be able to consult with one over the phone through their lab about Gamble's case if you are interested in other options.

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