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How long should I wait to give my dog Trifexis after flea shampoo?

Updated On September 23rd, 2025

Pet's info: Dog | Black Mouth Cur | Female | spayed | 1 year and 3 months old | 50 lbs

CARESHARE I just treated my dog for fleas with advantage shampoo. How soon can I give her the Trifexxus preventative? She was due for it when I found a flea on her but wasn't sure if I should give her both at the same time.

1 Answer

Most Helpful Answer

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Answered By Dr. Massimo Orioles, DVM, Cert AVP, MRCVS

Veterinarian

Published on January 23rd, 2019

I would suggest to ideally wait 7 days before giving any other treatment to be on the safe side. The two might be given together as they have different active molecules but I would recommend always to give them at different times (one week apart). Hope this answer was helpful, but please do not hesitate to contact us again on the forum or by requesting a consultation if you have any more questions or to discuss it any further. If this answer was helpful please let us know, this will be used to improve our service!

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