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Why is my dog trembling in sleep while on Doxycycline for tick fever?

Updated On September 23rd, 2025

Pet's info: Dog | German Shepherd | Male | unneutered | 1 year old | 75 lbs

Good afternoon, I own a 1 year old German Shepard, and he caught some sort of tick fever last week. His blood work at the vet resulted in a low platelet count. So, the vet suspected the fever, but the tick fever test came back negative. My dog's been taking Doxycycline and Predisone, and he's done much better. But I've noticed my dog tremble in his sleep, I suspect it to be the fever, but also suspect it to be the antibiotic. What is the likely-hood of the trembling being caused by Doxycycli

1 Answer

Most Helpful Answer

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Answered By Andrea M. Brodie, DVM

Veterinarian

Published on March 27th, 2018

Doxycycline would not normally cause trembling or any neurological problems. It does sometimec cause the dog (and people also) to not be hungry or get nauseous. I would not worry about the trembling in his sleep, he may be dreaming which might cause the trembling. Keep giving him the Doxycycline and prednisone as prescribed by your veterinarian, as tick borne diseases such as Anaplasmosis, and Ehrlichiosis can be lethal if not completely cured. Doxycycline is usually the best choice.

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