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My guinea pig has bronchitis. Is penicillin toxic? What are safe meds?

Updated On September 23rd, 2025

Pet's info: Small Animal | Guinea Pig | Male

Guinea pig has bronchitis. We were prescribed bicillin 5.But it's toxic

1 Answer

Most Helpful Answer

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Answered By Jessica Keay, DVM

Veterinarian

Published on November 12th, 2018

I am sorry to hear about your guinea pig! You are correct in that we don't normally prescribe Penicillin products in guinea pigs as they can kill the normal healthy bacteria in the GI tract leading to severe GI problems. I would recommend contacting your vet to see if they have other antibiotics available. In the US we most often use a drug called Baytril (enrofloxacin) or Tribrissen (trimethoprim sulfadiazine). Perhaps your vet does have other drug options available.

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