Updated On September 23rd, 2025
Pet's info: Dog | Mixed Breed Large (61lb +) | Male | 7 years and 10 months old | 73 lbs
My dog Pepe has been taking Pred since October 1. We had a week with the minimum dose (15 mg / q48 hours) but in the last blood test had a very large rise in liver enzymes (at the time of the analytical took 29 days taking Pred). When seeing these results, my vet wanted to perform an ultrasound that turned out ok: without inflammation. My vet says that that rise in enzym. is due to Pred. This is so? By the way, could I give metoclopramide to my dog for vomiting with these high liver values?
1 Answer
Published on November 10th, 2018
Hello, without knowing the reason for the Pred., I cannot comment fully of this particular situation, but yes, Pred. is often associated with the elevation of liver values. I would definitely have Piluko on a liver protectant like Sam-e with milk thistle ( we have Denamarin here in the US ). As for the vomiting, your vet may recommend the metoclopramide or another medication such as Cerenia to control it. You can also try ginger root as it does have anti-nausea properties. The dose is wide, from 15-200 mg/kg every 12 hours, so start low & look to find a ginger root capsule that contains no other ingredients, especially xylitol. Make sure you tell your vet if you decide to try this. Thanks for using Petco Pet Education Center, formerly Petcoach.
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