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My cat vomits, has foamy urine. Is Semintra safe without kidney disease?

Updated On September 23rd, 2025

Pet's info: Cat | American Shorthair | Male

Cat is vomiting every other day with foaming urine. Been to vet a couple of times and no cause has been found. Kidney's were strong when last checked two months ago. Vet gave me Semintra if I wanted to see if that helped. Is it safe to give him if it turns out he doesn't have kidney problems?

1 Answer

Most Helpful Answer

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Answered By Ann Dion, DVM

Veterinarian

Published on October 11th, 2018

Hello and welcome to Petco Pet Education Center, formerly Petcoach. Semintra has actions of decreasing blood pressure and decreasing the protein loss with kidney disease. Therefore, if no kidney disease is present, and no high blood pressure is present, then you might see signs of low blood pressure or changes in the sodium and potassium. These are unlikely to occur but possible. Foaming urine is a sign of protein in the pee. Has the urine been checked for protein? I would recommend a Urine Protein:Creatinine Ration to properly assess if protein loss is present. Checking the blood pressure is a good idea as well (although somewhat difficult to perform in stressed cats accurately). I would probably recommend starting on a kidney food as a early management/prevention vs. starting on Semintra, unless your vet has a high suspicion clinically that Nomar has kidney disease (weight loss, dehydration despite drinking/peeing a lot, overly dilute urine, etc.). Kidney values only go up once 75% of the kidneys are affected, so we have to rely on other indicators to catch kidney disease early. Talk to your vet about IRIS staging. Best of luck with Nomar, I hope he feels better soon.

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