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Why does my dog's paw keep getting an inflamed bump between toes?

Updated On September 23rd, 2025

Pet's info: Dog | Labrador Retriever | Female | spayed | 11 years and 10 months old | 45 lbs

Cleo has a bump inbetween her toes and has had antibiotics for it before as it has been infected and keeps getting inflamed as she keeps licking it. Her vet said it's down to arthritis but she is now on painkillers for that and the bump still keeps coming back. I'm going to try get her another appointment but would like another opinion.

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1 Answer

Most Helpful Answer

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Answered By Angel Alvarado, LVT

Licensed Veterinary Technician

Published on October 9th, 2018

It could have an allergic component or be an interdigital cyst. A closer physical exam and possibly x-rays of the paw would be recommended. Ruling out a foreign body (grass seed, awn, foxtail, etc) or tumor would also be recommended. If your veterinarian will not pursue a more definitive diagnosis, consider a different vet in the practice or a different clinic entirely. Discuss allergy testing, hydrolyzed diets, food elimination trials and even antihistamine use with the vet. It looks like Cleo will need antibiotics once again anyway. Use an e-collar (cone) to prevent licking which can delay healing and may introduce infection.

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