Does prednisolone cause dilute urine in cats? Is it bad for kidneys?

Question

My cat is on prednisolone for seasonal allergies/asthma. She has been off and on it since the end of July. Currently, I have her taking one quarter of a 5mg tab, every other day. My question is, does prednisolone affect the urine specific gravity as it tends to cause increased thirst. I have a refractometer and I try to monitor. She's just above 1.02. Naturally, I am concerned about kidney health and function. Pet's info: Cat | Russian Blue | Female | spayed | 10.5 lbs

Dr Stafford, BVetMed, MRCVS · Accepted Answer

Steroids interfere with antiduretic hormone which normally is responsible for resorbing water in the kidneys. Thus more water is lost in the urine making it much more dilute. This is likely why you are getting low readings for usg. If you are still concerned you could have your vet run an SDMA check on blood for early signs of kidney problems

Does prednisolone cause dilute urine in cats? Is it bad for kidneys?

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