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What's the best drug to calm my anxious cat before a vet visit?

Updated On September 23rd, 2025

Which is the better drug to calm a very anxious cat who has to visit the Veterinarian? My vet prescribed Acepromazine, but I've seen other info. suggesting that a Benzodiazapene such as Diazepam (Valium) or Alprazolam (Xanax) might be better. This is a last resort to get the cat to the Vet office (last time he was further traumatized as his crate broke open on the parking lot!) From what I've read the Benzodiazapenes seem to address the actual anxiety better. Thank you.

1 Answer

Most Helpful Answer

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Answered By Dr. Davis

Veterinarian

Published on October 5th, 2018

Actually now the recommend medication is gabapentin. Ask your veterinarian for some and give it before the visit. With this the cats are just mellow, easy to handle and not as drugged as with the other medications. Diazepam is not used much in cats now due to it causing liver problems. Apromazine can make them sedate but doesn’t reduce the aggression. I personally don’t find Xanax effective. Thanks for using Petco Pet Education Center, formerly Petcoach to help you care for your cat.

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