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My Maltese has high liver enzymes but acts normal. What could it be?

Updated On September 23rd, 2025

Pet's info: Dog | Maltese | Female | spayed | 11 years and 5 months old | 11 lbs

Our 11 year old Maltese went in for some blood work (getting ready for dental surgery) came back with liver/ pancreatic enzyme levels 6 times normal level. She is alert, still eating everything in site. Her CBC levels were normal. Vet is not ruling anything out. Any theories on what could be going on? I've read about PSS, common in these dogs, but that is usually diagnosed in their puppy years. She has a ultrasound appointment Saturday to figure out what is wrong.

1 Answer

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Answered By Laura Johnson VMD

Veterinarian

Published on March 14th, 2018

Hi, thanks for using Petco Pet Education Center, formerly Petcoach! Poor Hope! Causes on increased liver enzymes/pancreatic enzymes are: liver or gall bladder infection, inflammation of the liver, liver shunt (PSS) or microdysplasia, gall bladder mucocele/sludge or obstruction, pancreatitis, cancer of liver, gall bladder or pancreas, steroid or vacuolar hepatopathy from cushings disease. I am glad you have an ultrasound scheduled! Hopefully you will find the answer and get Hope on the road to recovery!

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