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Can sildenafil help my dog with megaesophagus stop regurgitating?

Updated On September 23rd, 2025

Pet's info: Dog | Labrador Retriever | Female | spayed | 1 year and 2 months old | 30 lbs

Is sildenafil a viable option to help dogs with megaesophogas gain weight and stop regurgitating?

2 Answers

Most Helpful Answer

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Answered By Daniel Fonza, DVM

Veterinarian

Published on March 12th, 2018

There was a recent study that looked into the use of Sildenafil and megaesophagus. At a recent conference held by an internal medicine specialist, they are now using Sildenafil in these cases to reduce regurgitation and are finding great improvement and a decrease in the amount of regurgitation. Here is a link to the paper. There were no comments on weight gain when using Sildenafil and no mention of this in the study. I hope this helps! You can show your veterinarian this research paper as well. We have used Sildenafil in several cases of megaesophagus now and they have shown much improvement since starting. Please let me know if you have any other questions or concerns and I would be more than happy to help you further! ( http://caninemegaesophagusinfo.com/wp-content/uploads/2017/06/Sildenfil-CIM-Full-1.pdf )

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Other Answers

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    Answered By Daniel Fonza, DVM

    Veterinarian

    Published on

    ( https://www.google.com/search?ei=k52mWtCkOomP0gLY3IKwCQ&q=sildenafil+italian+study+dogs+regurgitation+&oq=sildenafil+italian+study+dogs+regurgitation+&gs_l=psy-ab.3...8851.11632.0.12375.18.17.0.0.0.0.166.1629.9j7.16.0....0...1c.1.64.psy-ab..2.13.1361...33i160k1j33i21k1.0.--yLvILZK4E ) Click on the second link in the google search results. It is a PDF.

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