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Can antibiotics cause my pet's high blood count? Is he very ill?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed | Male | neutered | 9 years and 6 months old | 22 lbs

Mononucleosis and eosinophil blood count is on the high side after my pet began treatment on antibiotics and anti inflammatory medicine. Please see attached pictures image 1 for originally before treatment. Image 2 in the middle of treatment.In blood test the MONO and EOS are elevated Does ANTIBIOTICS Amoxicillin 250mg and enrofloxacin 50mg. Antiinflammatory Carprofen 25mg cause the two blood test result samples to rise. Also please help me analyze the blood tests to see if my pet is very ill

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Answered By Rodrigo Roca, DVM

Veterinarian

Published on August 30th, 2018

Hello, the elevations of the cells is very mild. It appears that she may have a mild infection, given that his eosinophils are high, the most likely cause may be associated with parasites. The medications should not cause the white blood cells to go up, instead, it should help decrease their number. Speak with your veterinarian about checking his stool for parasites and consider deworming him as well. Also check for heart worm disease. Hope this helps and best of luck.

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