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My cat has FIV and kidney failure. Why are her meds making her drowsy?

Updated On September 23rd, 2025

Pet's info: Cat | Bombay | Female | spayed | 3 years and 7 months old | 5.07 lbs

Mimi has fiv & recently got a diagnosis of renal failure. Based on advice here & vets in Pakistan,we started her IV yesterday,with antacids & anti-nausea & they even gave her an appetizer. I've attached the prescription. Both the appetizer cyproheptadine & anti-nausea (maropitant) have sedating effects. They didnt suit Mimi. It's been over 12 hours she's still a little drowsy & disturbed. I've put her on IV again to flush these meds out,but I'm going to ask the vet to stop cyprohep. Any advice?

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1 Answer

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Answered By Rodrigo Roca, DVM

Veterinarian

Published on August 29th, 2018

Hello, sorry to hear about Mimi. Based on those blood values, she has considerable renal disease. A creatinine of 8.6 likely requires hospitalization and medical support through injectable medications. Its unlikely that the oral formulations could take effect or that she will take them orally to help treat her. Most of the time, these patients require multiple medications to combat the kidney disease. In addition to the anti-nausea and appetite stimulant, they require antibiotics, IV fluids and other gastro-protectants. If the kidney disease continues to progress, they may even require dialysis. Ultimately, it sounds like the renal failure may be associated with her FIV, or that her FIV predisposed her to having a severe kidney infection. Your veterinarian may need to check her urine to look for any evidence of bacteria and potentially perform an abdominal ultrasound to asses her kidneys. Contact your veterinarian to speak about further diagnostics. Hope this helps and best of luck.

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