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My dog's epilepsy meds stopped working. What can I do?

Updated On September 23rd, 2025

Pet's info: Dog | Chihuahua | Male | neutered | 7 years and 11 months old

Hi so ceaser was back at the vets today His epilepsy pills are not working his fits have returned with a vengence. He now has a urinary tract and bowel infection and is on antibiotics. The vet is baffled as to why his pills have stopped working. Although ceaser is still eating and drinking he is just really depressed and sleeps alot. The vet thinks if his quality of life has changed maybe we should think about euthanasia. Im so sad and confused i dont know what to do am i being selfish

1 Answer

Most Helpful Answer

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Answered By Ricardo Fernandez, DVM

Veterinarian, Veterinary Oncology Resident

Published on August 3rd, 2018

Thanks for using Petco Pet Education Center, formerly Petcoach! I do not think that you are being selfish at all. You care about him which is good. It is common for dogs with epilepsy to eventually need more medications added to their anti-seizure medication protocols. There are several anti-seizure medications that can be considered including phenobarbital, potassium bromide, Keppra, zonisamide, among many others. I would encourage you to discuss with your veterinarian about other anti-seizure medications. Often times dogs with epilepsy respond favorably to other medications. Good luck and have a great day!

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