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Hiking dog: Can I combine Frontline Plus with a tick collar safely?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Small (up to 22lb) | Male | neutered | 5 years and 4 months old | 21 lbs

Hi. I will be going to Woodstock NY with my family, which includes my 20 pound 5 year old cockapoo, Winston. we have been using Frontline plus every month (in between the scapulae). I am concerned about Ticks since we will probably be doing a fair amount of hiking, I have read that Frontline Plus in addition to the Prevetic collar is ok, but Frontline plus in addition to the Seresto collar "you should ask a veterinarian” Do you feel the combo is ok, and that it might give better protection?

1 Answer

Most Helpful Answer

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Answered By Penelope Graben, DVM

Veterinarian

Published on July 4th, 2018

Hello! You should be able to use both Frontline and either a Preventic or Seresto collar, but only one collar. There should not be any interactions between any of the medications. I think using two preventives for hiking in the northeastern US is an excellent idea to prevent ticks and tick borne disease. I would also recommend looking into getting Winston vaccinated for Lyme disease as an additional precaution. I hope this is helpful! I hope you guys have a great, bug-free hiking trip! :) Thanks for using Petco Pet Education Center, formerly Petcoach!

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