My dog has jaundice and bleeding after treatment. Is it liver cancer?

Question

Ty; His reports4 BP;SUGAR;ECG;TEMP;URIN TEST::FOUND OK blood test inclsd(pls check from that only) After taking this medicine he now got jaundis too As i already told he got a unit blood from indie dog is that safe?Prescribed medicine till date is:: Zip vit ;sucroll;livotas;thombup, LISYBIN LARGE ALAMINR FORTE DOXYPET200 UDILIV300 VENOL AZATHIOPRINE along with daily dose of NS DNA D10 WITH .is that he is not safe ?is that liver cancer?pic aftr taking medicine b4 he dont ve any spot on area. Pet's info: Dog | Golden Retriever | Male | 9 years and 4 months old | 30 lbs

Stacey Anstaett, DVM · Accepted Answer

I'm sorry Meddy is sick. I am trying to understand exactly what is going on with him. It sounds like your vet is suspicious of an immune mediated disease (where Meddy's own immune system is malfunctioning and destroying her platelets (as well as possibly her red blood cells and/or white blood cells). A blood transfusion may have been required help Meddy survive. Let me briefly review the medications you've listed: *Zip vit- I am not familiar with this, but it seems to be a vitamin supplement. *I suppose "sucroll" may be the drug sucralfate, which is a medication that helps to decrease bleeding in the stomach and intestine. *Livotas is not something used in the US and I cannot find any information on it. *Thrombup is an herbal that may be beneficial when platelets are low (I don't have any experience with this one, and it is not generally used in the US) *Lisybin is a supplement for liver health. *Alamin R Forte is not something I have experience with but appears to be used for a number of different indications in India. *I assume Doxypet is doxycycline, which is an antibiotic commonly used to treat possible underlying infection that results in immune mediated cell destruction. Doxycycline also has some anti-inflammatory properties that can be helpful. *udiliv300 is ursodiol, which helps with bile flow from the gallbladder and through the liver *Venol is not a drug used in dogs in the US, so I am not sure what the purpose of this mediation would be for Meddy. *azathioprine suppressed the immune system and helps treat immune mediated diseases. Azathioprine can have negative side effects on the liver, so the liver protective medications listed may be to help try to minimize these negative effects on the liver. * I do not know what you mean by NS DNA D10. Regarding the pictures you've attached : The first picture is shows small spots of bleeding under the skin, which would commonly be seen with low platelet counts. The second picture looks like what is an amino acid supplement that can be given as an injection. I am not sure of the purpose of this medication for Meddy, but I don't see a reason it would cause harm. The third picture of the lab findings- shows the red cell count a little low (mild anemia), and there is no number for either the platelets or the total white blood cell count. Generally that means those counts are very low--too low for the machine to read. To try to answer your questions: I am not highly suspicious that this is liver cancer, but it is possible. We can see immune mediated cell destruction AS A CONSEQUENCE of cancer, so it may be that liver cancer, or another type of cancer, is the underlying cause. It is possible that the liver value abnormalities on the lab work are a side effect from the medication. You can talk to your vet about potentially having an abdominal ultrasound (sonogram of the belly) performed. This may help identify a tumor in the liver or elsewhere that may be the underlying cause of disease. The picture that you took with the spots on the skin-- this would be seen from low platelets. I suspect that the medications were all started BECAUSE of low platelets. It takes time to get that platelet count up, so bleeding will continue while platelets are low. So more bleeding will occur until the meds are working. I do not think that this is reaction to medications. (Having said that, unfortunately sometimes patients just do not respond well to treatment and we cannot get the platelet count up despite our best efforts). Regarding the jaundice that you've seen after the medication was given-- again I doubt this was a result of the medication. If his red blood cells are being destroyed by his immune system, this will result in jaundice. Additionally, following transfusion (even from a known blood source) jaundice is common. I hope that information helps, I can try to help more with a consult. Thank you for asking Petco Pet Education Center, formerly Petcoach!

My dog has jaundice and bleeding after treatment. Is it liver cancer?

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