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My dog has a chronic aspergillus sinus infection. What can I do?

Updated On September 23rd, 2025

Pet's info: Dog | Poodle | Male | neutered | 10 years old | 160 lbs

My 10 year old Standard Poodle has an aspergillus sinus infection X 1 year+. His nose is tender, & red; he has an ongoing copious yellow-green nasal discharge, reverse sneezing, and coughing. He has had 3 trepination procedures, with an azole instilled into his sinuses. The last one did result in some improvement, but he is definitely still affected by it. After the last procedure, he was started on 148 mg fluconazole capsules twice daily, with liver enzymes monitored. What can be done?

1 Answer

Most Helpful Answer

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Answered By Dr. Heidi DVM, CVA, CCRT, CVTP, CVSMT, CVCH

Veterinarian, Certified Veterinary Acupuncturist, Certified Canine Rehabilitation Practitioner

Published on July 1st, 2018

It sounds like your veterinarian is doing a great job with a difficult disease. I'm glad to hear that Wiley seems to be a little better after his last procedure. I think adding oral anti-fungal medication sounds like a great idea, so I think we will just need to wait to see adding the Fluconazole is sufficient. Sometimes we need to combine oral anti-fungal medications. My latest case of aspergillus is being treated with Terbinafine and Voriconazole which are expensive, but seem to be working well. So, if theFfluconazole does not seem to show improvement, you can discuss other oral anti-fungals with your veterinarian. Good luck! I hope that was helpful. Thanks for using Petco Pet Education Center, formerly Petcoach.

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