Petco Text Logo
Petco Pet Logo

Does a very high blood test level mean my dog's Cushing's is advanced?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed | Female | spayed | 9 years and 7 months old | 21 lbs

My dog was given a blood test to check for Cushing's disease and it came back that she needed more tests and she's booked in for an ultrasound. whatever they tested for, it came back very high which indicated cushions. I think the level had to be around 250 or something, hers were 1570 . The vet didn't tell me what that meant and I'm not quite sure what it was they tested. Basically, my question is, does that level indicate the disease is more advanced?

1 Answer

Most Helpful Answer

Image profile

Answered By Dr. B. DVM, DACVIM (Oncology)

Veterinarian

Published on June 30th, 2018

Cushing's or Hyperadrenocorticism is a fairly common endocrine disease in dogs. It can be caused by a bit of overactive tissue in the brain (in the pituitary gland, which is the master ruler of hormone secretion in the body) or a mass in an adrenal gland (sits by the kidneys, secretes hormones as directed by the pituitary gland). Basically what happens is an excess of a hormone in the body, usually a steroid called cortisol, if it is traditional Cushing's. This then causes some symptoms in the pet, blood work changes, and sometimes other changes like high blood pressure. I suspect based on the value that you report that this was a liver enzyme elevation call ALP. This very commonly occurs in pets that have Cushings, but is not specific for Cushing's and elevation can be caused by other disease processes. This value does not correlate with severity of disease as many dogs have a high value. It sounds like your vet is on the right track by recommending an ultrasound to look at the adrenal glands and also the rest of the abdominal organs to rule out other disease processes. Ultimately Cushing's Disease has to be diagnosed by some sort of endocrine testing which your vet may recommend as well. Treatment if then based on what type of Cushing's disease is present. I hope this helps and thank you for using Petco Pet Education Center, formerly Petcoach!

Vote icon

1Pet Parents found this answer helpful

image
Have A Vet Question?

Book an appointment with the pros – our expert vets are here to help.

Sponsored