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My dog survived parvo. Can he get parvovirus again with diarrhea?

Updated On September 23rd, 2025

Pet's info: Dog | Great Dane | Male | unneutered | 3 years and 4 months old | 220 lbs

My dog had parvovirus over two years ago as a puppy, despite being vaccinated. He survived, but it was touch-and-go for over a week. A couple of days ago, he vomited some clear fluid but seemed fine otherwise. Yesterday, he developed severe diarrhea which has persisted. It has that "parvo smell", but it is yellow, not mahogany-colored. He doesn't seem to be very sick -- just a bit tired. His appetite is reduced, but he's eating. Could he be suffering from parvovirus again?

1 Answer

Most Helpful Answer

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Answered By Sara Farmer, DVM

Veterinarian

Published on June 11th, 2018

It would be extremely unlikely for a dog that has survived parvovirus to be affected again - the virus provides such excellent immunity that some veterinarians will take serum from recovered dogs to give transfusions to those affected with the disease (although this may or may not help). There are many other diseases that could cause diarrhea with that distinctive parvoviral smell. If the diarrhea is severe I'd recommend seeing your veterinarian who can run some tests to determine what might be causing his diarrhea this time around and start some treatment.

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