My cat has chronic diarrhea, meds didn't work, fecal negative. Is it serious?

Question

Hi! metronidazole and prednisolone did not ease chronic diarrhea in my cat. Can that rule out anything? Fecal test negative. Cat is acting and eating normally. No vomiting, no blood in stool, no dehydration. Hyperthyroid is under control. He does munch on grass whenever he gets a chance. Usually something serious like cancer or obstruction, he would show signs of pain, correct? Thank you. Pet's info: Cat | Korat | Male | neutered | 13 years and 5 months old | 9.6 lbs

Ann Dion, DVM · Accepted Answer

Hello and welcome back! Prednisolone not working suggests that IBD is not the problem. Metronidazole is a broad spectrum antibiotic and treatment for giardia, therefore likely the problem wasn't a bacterial or giardia infection. A negative fecal rules out other parasites like worms or coccidia. If Beau has hyperthroidism then the diarrhea could be related to this, and tweaking of the medication might be required. He still could have cancer in the GI tract (lymphoma) which doesn't always cause an obstruction or pain, especially not right away. He could also have food allergies, or liver disease, or pancreas disease. There would be pain with an obstruction, and clinically this doesn't sound like an obstruction, but you can have no pain with cancer. Best of luck with Beau.

My cat has chronic diarrhea, meds didn't work, fecal negative. Is it serious?

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