My dog has a high fever, low platelets, and won't eat. What's wrong?

Question

My dog is 3 years old. He has continuous fever of 105.8 for 4 days. He's currently receiving injection of Enrofloxacin , prendisolone and has platelet count of 31k. He has stopped eating solid food and is on liquid diet like milk, yoghurt. Pet's info: Dog | American Bulldog (duplicate) | Male | unneutered | 44.09 lbs

Dr. Massimo Orioles, DVM, Cert AVP, MRCVS · Accepted Answer

The problem here is to establish the underlying cause of thrombocytopenia (low platelets). Immune-mediated thrombocytopenia is one of the most common causes. This process usually occurs in the spleen although the liver also plays a role. Thrombocytopenia develops as platelet destruction exceeds compensatory production by the bone marrow. Immune-mediated thrombocytopenia can be classified as primary or secondary. Secondary processes can be caused by infective diseases or tumors very commonly. Usually to determine a diagnosis more tests needs to be performed like abdominal ultrasound and chest x rays. Infective diseases like Ehrlichia, Anaplasma spp for example should be ideally evaluated as well. Hope this answer was helpful, but please do not hesitate to contact us again on the forum (where you can post pics of the blood tests) or by requesting a consultation if you have any more questions or to discuss it any further.

My dog has a high fever, low platelets, and won't eat. What's wrong?

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