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Cat on metronidazole: Explosive diarrhea normal? Keep giving meds?

Updated On September 23rd, 2025

Pet's info: Cat | Korat | Male | neutered | 13 years and 5 months old | 9.6 lbs

Hi, my cat has been having chronic loose stools and was put on metronidazole. After just one day of the antibiotics, he started to have explosive diarrhea. Is that normal and should I continue with the meds?

4 Answers

Most Helpful Answer

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Answered By Jyothi Alagappan

Veterinarian

Published on June 2nd, 2018

Hi and thank you for using PetCoach. I am sorry to hear that Beau is having diarrhea. Since, Beau has only been on metronidazole for one day, I would continue it as it may not have started to work yet. It typically takes 24-48 hours to see any changes. However, if Beau stops eating, is lethargic or has blood in his stool, I would reach out to your veterinarian again and let them know. Beau may need another physical exam or other medications. Here is an article on diarrhea in cats that may be helpful for you and Beau: https://www.petcoach.co/article/diarrhea-in-cats/ Good luck and I hope he feels better soon!

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    Answered By Jenny, DVM

    Veterinarian

    Published on December 30th, 2017

    All you can do is continue the medication as previously directed--more doses should help, it just may be too soon to see right now. I would look at a local pet store for a feline probiotic to add to the food as this can help repopulate the normal bacterial population and possibly change her to a sensitive stomach formula food.

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    Answered By Lindsey Edwards MVB, BSc, IVCA

    Veterinarian

    Published on December 21st, 2019

    Without a full history as to why a diet change was prescribed it is impossible to recommend reverting back. Metronidazole can cause marked diarrhoea in patients which may be triggering the symptoms. I recommend continuing as prescribed until you can contact your Vets office to discuss the changes in her condition and decide the best way forward

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    Answered By Stacey Anstaett, DVM

    Veterinarian

    Published on May 29th, 2019

    My understanding of your question os taht you are concerned about your cat having loose bowel movements, her stool is loose like she has some mild diarrhea. Am I understanding you correctly? If so, then you can try adding a probiotic; there are some good ones formulated for cats. Ideally, take Chikoo to a veterinarian. If your vet diagnoses Giardia or an overgrowith of bacteria, often the medication metronidazole is prescribed. Metronidazole is not labeled for use in animals, though it has been used safely and effectively. See additional information here: https://cdn.ymaws.com/www.aavpt.org/resource/resmgr/imported/metronidazole.pdf Thank you for asking PetCoach!

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