Updated On September 23rd, 2025
Pet's info: Dog | Australian Shepherd - miniature | Male | neutered | 1 year and 2 months old | 24.7 lbs
I have a 14-mo-old mini Australian Shepherd, tested clear on MDR1 gene mutation, no known health issues. He’s taken Trifexis for 12 mos for flea/heartworm, Simparica added 3 mos ago for ticks. Meds are given with meals 1-2 wks apart. We live in an area where heartworm & ticks are a problem so I need year-round preventives. Sentinel has been suggested instead of Trifexis but my pup weighs between 24.5-25.5 lbs which is right at the dosing boundary. What’s the protocol for choosing the right dose?
1 Answer
Published on March 3rd, 2018
Sentinel has no tick coverage and does not kill fleas. It only sterilizes the eggs. I always go up a size to be safe as most dogs gain weight but rarely lose weight. It has a good safety margin so using the 25-50 pounds medicine would be best. You will continue to need the Simparica or nexgard with this
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