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Can I give Cerenia & Buprenorphine to senior cat with kidney disease?

Updated On September 23rd, 2025

Is it acceptable to administer Cerenia and Buprenorphine within the same day in a 17 year old cat with kidney deficiency? She also shows signs of vestibular disease and the Cerenia really helps her. Use of the Buprenorphine is quite rare, but we use it as needed for pain. ie...sometimes she moans and groans after eating canned food like fish flavored Weruva--thus, the Buprenorphine.

2 Answers

Most Helpful Answer

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Answered By Destini R. Holloway, DVM

Veterinarian

Published on February 19th, 2017

Poor girl! Yes you can safely give Cerenia and Buprenorphine on the same day and even at he same time, if needed. If she has kidney disease then subcutaneous fluids will also help with that. I know th Cerenia helps with her vestibular disease because it mostly is helping with her nausea. However Cerenia is only safe to give for 5 consecutive days. After that time frame I would suggest asking your vet for motion sickness medication (Dimenhydramine) that can be given long term, if needed. I hope your kitty feels better soon!

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    Answered By Dr. Melanie, BVSc MS

    Veterinarian

    Published on

    Yes, you can administer the Cerenia and buprenorphine on the same day if needed as long as both were prescribed by a vet for her. While buprenorphine can have interactions with other drugs, cerenia is not listed as one of those drugs.

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