Updated On September 23rd, 2025
Pet's info: Dog | Mixed Breed Medium (23 - 60lb) | Female | unspayed | 1 year and 5 months old | 31 lbs
My Border Collie has been developing a depigmentation on her black nose over the course of almost 2 weeks now. At first thought it was a wound given to her through a fight with our cat but it continues to grow. She does not seem to be bothered by it, however she has been eagerly biting at the nails of her paws frequently over the past couple months which is odd behavior compared to before. She is only 1 and half years of age. From some of what I have read I am extremely concerned.
1 Answer
Published on February 15th, 2017
There are breeds of dogs that are prone to a seasonal lightening of the nasal planum (the hard, tough, hairless end of their nose). Sometimes referred to as “Snow Nose” these dogs (Siberian Huskies, Labradors and Golden Retrievers) can have darker noses in the summer months and lighter noses in the winter. These same breeds plus German Shepherds, Samoyeds, Afghan Hounds and Dobermans (among others) can also experience a gradual or waxing and lightening or fading of their nose color over time. This condition is known as “Dudley Nose." Vitiligo is a progressive disease in which the melanocytes are gradually destroyed causing unpigmented areas on the skin. They develop pigment loss from their skin or hair on their heads, but it can occur in other locations too. In some cases, antibodies against melanocytes have been identified in the serum of infected dogs indicating an immune component to the disorder. And skin biopsies of the affected areas will typically reveal a total lack of any remaining melanocytes. What all three of these causes for depigmentation have is common is the fact that they are not a disease that can bother or hurt your dog at all. There is no reason to worry about them and there is nothing to be done to ‘correct’ them. The depigmentation is purely cosmetic. Some depigmentation is cause for concern. For instance, any contact dermatitis/irritation can cause depigmentation as can certain chemicals in rubber that can affect the production of melanin pigment where the rubber touches the skin. The administration of certain drugs like ketoconazole, procainamide, and vitamin E have been reported to cause generalized changes in coat color in dogs, and injections of other drugs (glucocorticoids, for instance) can cause localized loss of pigment. Additionally, hormonal disorders (imbalances of thyroid, adrenal or sex hormones) can alter pigmentation as can bacterial and fungal infections and even cancers (neoplasias). Immune-mediated diseases also occur in dogs where the dog’s own antibodies attack different parts of the skin resulting in depigmentation. I recommend getting your dog seen by your vet just to be safe. She is young for some of these conditions to occur, but nothing is impossible.
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