my dog had her annual shots yesterday afternoon.Shortly after she began to act oddly, tail down and trembling, has lasted all night.What should I do? Pet's info: Dog | Mixed Breed Small (up to 22lb) | Female | spayed | 9 years and 4 months old | 20 lbs

Such a reaction to vaccinations are not completely uncommon, these usually resolve without treatment within 24 hours. if it has been more than 24 hours and she is still not herself i would advise you to contact your vet, sometimes pain killers are needed. in some more rare cases vaccination reaction can cause more long lasting issues, but this is extremely rare.

I'm so sorry to hear ButterCup is having problems! I would recommend you take her to your vet to be evaluated as soon as possible. I am very concerned that she appears weak and can't seem to stand up. This could indicate a life threatening problem that needs to be addressed as soon as possible! If she just received a vaccination today, it is possible she is having a vaccine reaction. Vaccine reactions are uncommon but do occur and we want to treat them as soon as possible with appropriate drugs. If she received a vaccination days ago, then there may be something else going on with her and she may be in pain. Without doing an exam it is impossible to tell what the underlying cause is, but based on your description I would get her in to your vet quickly. If you can video the twitch she is doing that also would be helpful to show your vet in case she stops doing it by the time she is seen. I hope ButterCup is on the mend soon!

Getting vaccines can be stressful to the puppy and can cause some pain. This should pass in 24-48 hours. You can try putting a cold compress where she received her shots to see if that helps. Apply it for 5-10 minutes at a time a couple of times during the day. Otherwise keep her warm and comfortable, and make sure she is eating and drinking. If the shaking doesn't away in 48 hours, or she develops other signs such as vomiting, diarrhea, facial swelling, and/or difficulty breathing, take her into a vet. Best of luck, I hope this helps.