My 20 lb dog accidentally took 50mg Benadryl. Is it an emergency?

Question

I accidentally gave my 20 lb dog 50 mg of Benadryl. Will she be okay?

Dr. Melanie, BVSc MS · Accepted Answer

Oh no! So this dose is over twice the recommended dose for a dog her weight. Unfortunately, the lethal dose for oral diphenhydramine (Benadryl) in dogs has not been studied, but it's believed the minimum needed could be as few as four tablets according to a study published in 2014 in the Canadian Veterinary Journal. It would be best for you to take your dog into the vet now to have vomiting induced. While it is only two tablets, because the lethal dose hasn't been determined, it's better to be safe than sorry. I would find a vet on call to see her now, or take her into an ER vet.

My 20 lb dog accidentally took 50mg Benadryl. Is it an emergency?

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